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Could these celiac trials have detected their drugs? TAK-101 prevented 71% of gluten injury and was written up as a failure. At 13 patients per arm it needed 95%. Endpoint noise is not constant: SD = 0.40 + 0.30 × injury.
Python
#biostatistics#celiac-disease#clinical-trials#collaborate#data-science#learn#meta-research#python#reproducible-research#statistical-power#student-project
Add interactive Streamlit or Gradio UI for running trial simulations about 1 month ago
enhancement help wanted
Could these celiac trials have detected their drugs? TAK-101 prevented 71% of gluten injury and was written up as a failure. At 13 patients per arm it needed 95%. Endpoint noise is not constant: SD = 0.40 + 0.30 × injury.
Python
#biostatistics#celiac-disease#clinical-trials#collaborate#data-science#learn#meta-research#python#reproducible-research#statistical-power#student-project